Tubulointerstitial nephritis ( TIN) was first in female Wistar rats by immunization with rabbit tubular basement membrane ( TBM) complete Freund's adjuvent and pertussis vaccine diphtheria tetanus toxoid mixture. 选用兔肾小管基底膜(TBM)、完全福氏佐剂及百白破疫苗免疫雌性Wistar大鼠,成功地建立了肾小管间质性肾炎(TIN)模型。
Detect antibody level by ELISA and IHA from 1014 antiserum samples of persons by complete tetanus toxoid vaccination, compare serum collecting rates and collecting rates in accordance with the standard and the correlation in between the two methods and animal test. 应用酶联免疫法(ELISA)和间接血凝法(IHA)对1014份破伤风类毒素全程免疫后人血浆进行抗体水平检测,比较两者的收浆率、收浆符合率以及与动物实验的相关性。